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Triisopropylsilyl Chloride Cas 13154-24-0
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Triisopropylsilyl Chloride Cas 13154-24-0
  • name

Triisopropylsilyl Chloride Cas 13154-24-0

Brand Name: CFI
Model Number: -
MOQ: 1000 kilograms
Price: US $10.0 - 30.0 / Kilogram
Detail Information
Product Description
Detail Information
Place of Origin:
China
CAS No.:
13154-24-0
Other Names:
Triisopropylsilyl Chloride
MF:
C9H21ClSi
EINECS No.:
603-492-0
Type:
Syntheses Material Intermediates
Purity:
99%
Application:
Intermediate
Appearance:
Liquid
Highlight:

Triisopropylsilyl Chloride pharmaceutical intermediate

,

Triisopropylsilyl Chloride CAS 13154-24-0

,

Triisopropylsilyl Chloride chemical reagent

Product Description

Triisopropylsilyl Chloride (TIPS-Cl) CAS 13154-24-0 – Reagent Grade Silylation Reagent

**Product Description**

Triisopropylsilyl Chloride is a colorless liquid silylating reagent used to install the bulky triisopropylsilyl (TIPS) protecting group on alcohols, alkynes and other nucleophiles. TIPS protecting groups confer steric protection and enhanced stability under many reaction conditions, making TIPS-Cl a standard reagent in medicinal chemistry and fine chemical synthesis. The reagent is moisture sensitive and corrosive — use dry solvents, inert atmosphere and appropriate acid scavengers when silylating.

**Applications**

  • Protection of alcohols and alkynes (TIPS protection) during multi-step synthesis
  • Protecting-group strategies in API route development and medicinal chemistry
  • Silylation to improve lipophilicity and chromatographic properties

**Technical Specifications**

Parameter Specification
CAS Number 13154-24-0
Purity (GC) ≥ 95–99% (grade dependent)
Molecular Formula C₉H₂₁ClSi
Molecular Weight 192.80 g/mol
Appearance Colorless to pale-yellow liquid
Density (25 °C) ~ 0.90–0.903 g/mL
Boiling Point ~ 198 °C (739 mmHg) — literature value

**Packaging & Storage**

Typically supplied in sealed steel drums (25–200 kg) or IBCs for bulk and in small amber bottles for R&D. Store tightly sealed under inert gas or in moisture-free containers, in a cool, dry, well-ventilated area away from water and protic solvents.

**Why Choose Chemfine?**

  • Reagent grades with traceable COA and GC assay
  • Technical support for silylation protocols and scaling
  • Flexible packaging from lab samples to bulk IBC shipments

**FAQ**

Q1: How should TIPS-Cl be handled safely?
A1: Use under inert atmosphere (N₂ or Ar) with dry solvents; wear appropriate PPE and work in a fume hood; use a base (e.g., imidazole or pyridine) to neutralize HCl generated during silylation. Consult SDS for full guidance. :contentReference[oaicite:19]{index=19}

Q2: Can TIPS-Cl be shipped internationally?
A2: Yes — but it is typically classified with chlorosilanes (corrosive, UN 2987) and requires appropriate packaging and documentation for transport (ADR/IMDG/IATA). Check the supplier SDS and local transport rules. :contentReference[oaicite:20]{index=20}

Tags: 

cas rn 108-39-4  

cas no of 121-88-0  

2-Amino-5-Nitrophenol 99

Good price online

Products Details

Home > Products >
Pharmaceutical Intermediates
>
Triisopropylsilyl Chloride Cas 13154-24-0
All Category

Organic Chemistry Solvents

Coating Additives

Electronic Grade Chemicals

UV Photoinitiator

PPG Polypropylene Glycol

Pharmaceutical Intermediates

Polyether Amine

Cosmetic Chemicals

Chemical Pigment

Chemical Dyestuff

Food Additives

Agrochemical Intermediates

Paper Coating Chemicals

Miscellaneous Chemical
Triisopropylsilyl Chloride Cas 13154-24-0
  • name

Triisopropylsilyl Chloride Cas 13154-24-0

Brand Name: CFI
Model Number: -
MOQ: 1000 kilograms
Price: US $10.0 - 30.0 / Kilogram
Detail Information
Product Description
Detail Information
Place of Origin:
China
Brand Name:
CFI
Model Number:
-
CAS No.:
13154-24-0
Other Names:
Triisopropylsilyl Chloride
MF:
C9H21ClSi
EINECS No.:
603-492-0
Type:
Syntheses Material Intermediates
Purity:
99%
Application:
Intermediate
Appearance:
Liquid
Minimum Order Quantity:
1000 kilograms
Price:
US $10.0 - 30.0 / Kilogram
Highlight:

Triisopropylsilyl Chloride pharmaceutical intermediate

,

Triisopropylsilyl Chloride CAS 13154-24-0

,

Triisopropylsilyl Chloride chemical reagent

Product Description

Triisopropylsilyl Chloride (TIPS-Cl) CAS 13154-24-0 – Reagent Grade Silylation Reagent

**Product Description**

Triisopropylsilyl Chloride is a colorless liquid silylating reagent used to install the bulky triisopropylsilyl (TIPS) protecting group on alcohols, alkynes and other nucleophiles. TIPS protecting groups confer steric protection and enhanced stability under many reaction conditions, making TIPS-Cl a standard reagent in medicinal chemistry and fine chemical synthesis. The reagent is moisture sensitive and corrosive — use dry solvents, inert atmosphere and appropriate acid scavengers when silylating.

**Applications**

  • Protection of alcohols and alkynes (TIPS protection) during multi-step synthesis
  • Protecting-group strategies in API route development and medicinal chemistry
  • Silylation to improve lipophilicity and chromatographic properties

**Technical Specifications**

Parameter Specification
CAS Number 13154-24-0
Purity (GC) ≥ 95–99% (grade dependent)
Molecular Formula C₉H₂₁ClSi
Molecular Weight 192.80 g/mol
Appearance Colorless to pale-yellow liquid
Density (25 °C) ~ 0.90–0.903 g/mL
Boiling Point ~ 198 °C (739 mmHg) — literature value

**Packaging & Storage**

Typically supplied in sealed steel drums (25–200 kg) or IBCs for bulk and in small amber bottles for R&D. Store tightly sealed under inert gas or in moisture-free containers, in a cool, dry, well-ventilated area away from water and protic solvents.

**Why Choose Chemfine?**

  • Reagent grades with traceable COA and GC assay
  • Technical support for silylation protocols and scaling
  • Flexible packaging from lab samples to bulk IBC shipments

**FAQ**

Q1: How should TIPS-Cl be handled safely?
A1: Use under inert atmosphere (N₂ or Ar) with dry solvents; wear appropriate PPE and work in a fume hood; use a base (e.g., imidazole or pyridine) to neutralize HCl generated during silylation. Consult SDS for full guidance. :contentReference[oaicite:19]{index=19}

Q2: Can TIPS-Cl be shipped internationally?
A2: Yes — but it is typically classified with chlorosilanes (corrosive, UN 2987) and requires appropriate packaging and documentation for transport (ADR/IMDG/IATA). Check the supplier SDS and local transport rules. :contentReference[oaicite:20]{index=20}

Tags: 

cas rn 108-39-4

cas no of 121-88-0

2-Amino-5-Nitrophenol 99

15312225715
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