LiHMDS Lithium Bis(trimethylsilyl)amide Liquid Cas 4039-32-1

Organic Chemistry Solvents
June 10, 2025
Category Connection: Organic Chemistry Solvents
Brief: Discover LiHMDS (Lithium Bis(trimethylsilyl)amide) CAS 4039-32-1, a versatile non-nucleophilic base for organic and pharmaceutical synthesis. Learn about its applications in enolate formation, metalation reactions, and more.
Related Product Features:
  • LiHMDS is a strong, non-nucleophilic base ideal for enolate formation in ketone/ester chemistry.
  • Widely used in pharmaceutical synthesis for producing intermediates and APIs.
  • Facilitates lithiation of aromatics under mild conditions.
  • Suitable for base-sensitive substrates due to its non-nucleophilic nature.
  • Appears as a colorless to light yellow liquid with high solubility in THF and hexane.
  • Stored under inert gas at low temperatures (0-5°C) to maintain stability.
  • Available in 20L and 200L steel or fluorinated drums for bulk orders.
  • Offers a purity of ≥ 99.0% with reliable QC support and COA provided.
Faqs:
  • Is LiHMDS moisture sensitive?
    Yes, LiHMDS must be handled under an inert atmosphere and dry conditions to prevent degradation.
  • Can you provide LiHMDS in bulk drums?
    Yes, we offer LiHMDS in 200L drum options for large-scale buyers.
  • Is a sample of LiHMDS available?
    Small samples (100-250 mL) can be arranged for qualified customers upon request.